Consulting
Bio-Spring was founded
by scientists with
extensive experience in
biotech. We offer
assistance with all
phases of your
product-development
project in the areas of
biopharmaceuticals,
protein reagents,
diagnostics, cosmetics
and nutraceuticals, and
industrial enzymes,
among others. Our
operating philosophy is
to provide customers
with the knowledge,
experience, and
judgement at the level
of interaction you’d
expect from your own R&D
organization.
Bio-Spring’s consulting
services cover a wide
swath of modern
biotechnology. For
example, a few of our
services include the
prioritization and
selection of therapeutic
targets, DNA construct
design and cloning, the
design of screening
experiments, the cloning
and expression of
recombinant proteins,
the selection and design
of unit operations,
scale-down or scale-up
of commercial
production, and enabling
and ensuring lot-to-lot
consistency.
Bio-Spring can even help
you engineer your new
protein to accomplish
specific goals,
including increasing
yields and efficacy,
improving druggability,
attenuating aggregation,
and other such features.
On the downstream side,
Bio-Spring can optimize
unit operations such as
extraction, refolding,
and capture through
dead–end filtration,
ultrafitration/dialfiltration,
resin screening,
chromatographic
condition and sequence
selection, and polish
chromatography. We
can also recommend
improvements to existing
or potential
chromatography,
filtration, and other
equipment systems, as
well as help you
evaluate custom
chromatography resins to
suit the purification
demands required for
final product
specifications. And we
can help you remove host
and product-related
contaminants to bring
your product into the
desired range.
One of Bio-Spring’s
particular strengths is
partnering closely and
confidentially with
clients in providing
timely and relevant
support for the project
at hand. We can
perform as an integral
member of your team to
help develop novel
products during all
phases of the cloning,
expression,
purification, analysis,
and formulation stages
to ensure that you meet
the required level of
final bulk or FDF
product quality.
What we don’t give you
is the costly overhead
from maintaining your
own R&D facility for
molecular biology and
protein production.
If you need to do a
quick proof-of-concept
experiment, our
resources are at your
disposal.
Call us
today to learn how we
can help you!